Properties, principle of operation
A broad-spectrum antibiotic is prescribed for the treatment of bacterial lesions only if there are no contraindications for the use of the composition.
Farmazin for cats
It is unacceptable to violate the course of therapy, as this leads to the formation of bacteria resistant to Farmazin, which significantly complicates further treatment. The composition is effective against most gram-positive and gram-negative bacteria (spp).
The main component of the drug, tylosin, has an inhibitory effect on protein synthesis in bacterial cells.
This allows you to stop the reproduction of the pathogen in a short time and destroy it with minimal harm to the animal’s body. The effect of tylosin is pronounced. The active components of the drug quickly penetrate the blood after its administration and are distributed throughout the body.
The maximum concentration of the antibiotic during accumulation is achieved in the lungs, kidneys and liver. The medicine is excreted in urine and feces.
If, after 3 days from the start of treatment, the animal’s condition does not improve, then it is necessary to urgently visit a veterinarian.
It is highly likely that the medication will need to be replaced with another drug. If possible, to determine the effectiveness of Farmazin, a bacterial culture of a smear taken from the throat or nose during inflammation of the respiratory system is carried out on a nutrient medium.
Be sure to read:
When to inject Fosprenil for cats - antiviral: instructions and dosage
Farmazin instructions for use
FARMAZIN 50 (Pharmasin 50)
COMPOSITION AND RELEASE FORM Farmazin 50 is a medicinal product containing the antibiotic tylosin as an active substance in the form of a base in an organic solvent. Farmazin 50 contains 50 mg of tylosin in 1 ml. The drug is a pale yellow injection solution. They are produced in 50 ml bottles, which are placed in cardboard boxes.
PHARMACOLOGICAL PROPERTIES Tylosin is an antibiotic from the macrolide group, active against most gram-positive and some gram-negative bacteria, including staphylococci, streptococci, corynebacteria, clostridia, pasteurella, erysipelothrix, spirochetes, chlamydia, Treponema chiodysentery and mycoplasmas. When administered intramuscularly, the antibiotic is well absorbed from the injection site into the blood and penetrates almost all organs and tissues of the body. The highest levels of tylosin are achieved in the lungs, liver, mammary glands and kidneys. After a single injection, the therapeutic concentration of the antibiotic remains in the body for at least 20 hours. In addition, due to the peculiarities of the mechanism of action, Farmazin 50 selectively accumulates in tissues with low pH values, that is, in areas of inflammation, providing a targeted effect. Farmazin 50 also exhibits nonspecific immunostimulating and immunomodulating effects due to the inhibition of cytokines, activation of plasma cells and antibody production, activation of leukocyte chemotaxis and proliferation of lymphoid elements. Farmazin 50 accumulates in exceptionally high concentrations in the lysosomes of neutrophils, ensuring the completion of phagocytosis and rapid disposal of bacterial pathogens. The special composition of the organic solvent in the injectable Farmazin ensures high storage stability, optimal consistency for comfortable filling of the syringe and absolutely painless injections for the animal. The drug is excreted from the body mainly in feces, and in smaller quantities in urine and milk.
INDICATIONS Prescribed for the treatment of bronchopneumonia of cattle and small ruminants, pigs, dogs and cats, enzootic pneumonia, arthritis, dysentery, atrophic rhinitis of pigs, infectious agalactia of sheep and goats, mastitis of cattle, skin and surgical infections, as well as for the prevention and treatment of secondary infections in viral diseases.
DOSES AND METHOD OF APPLICATION Farmazin 50 is administered to animals only intramuscularly once a day for 3-5 days in the following doses: cattle - 8-10 mg of active substance per 1 kg of animal weight, pigs - 10-12 mg of active substance per 1 kg of animal weight, sheep, goats, dogs and cats - 5-10 mg of active substance per 1 kg of animal weight. When repeated use, it is necessary to change the injection site.
SIDE EFFECTS Very rarely, allergic reactions in pigs are possible in the form of erythema, itching, respiratory phenomena, mild swelling with slight prolapse of the rectum, which quickly disappear after stopping the use of the drug.
CONTRAINDICATIONS Increased individual sensitivity to tylosin. It is not recommended to use Farmazin 50 simultaneously with tiamulin, clindamycin, chloramphenicol, penicillins (especially ampicillin and oxacillin), cephalosporins and lincomycin due to a pronounced decrease in the antibacterial effect of tylosin.
SPECIAL INSTRUCTIONS Slaughter of animals for meat that have been treated with Farmazin 50 is permitted no earlier than 8 days after stopping the administration of the drug. The meat of animals forcedly killed before the expiration of the specified period is used to feed carnivores or to produce meat and bone meal. Milk obtained from animals during the period of use of Farmazin 50 and until 4 days after the last administration of the drug is prohibited from being used for food purposes. This milk can be used to feed animals.
STORAGE CONDITIONS With precautions (list B). In a dry place, protected from light and out of reach of children and animals, at a temperature of 5 to 25 °C. Shelf life: 3 years.
MANUFACTURER Huvepharma AD, Bulgaria. Representative office in Russia: Address: 115191, Moscow, 4th Roshchinsky proezd, 19, room. 604. Tel./fax
Farmazin 500 powder
FARMAZIN water soluble powder
COMPOSITION AND RELEASE FORM Farmazin is a water-soluble powder, 1 g of which contains 500 mg of the antibiotic tylosin tartrate and filler. In appearance it is a hygroscopic fine-grained powder from white to cream color, with a specific odor and bitter taste. Produced in plastic jars of 25 g and 200 g.
PHARMACOLOGICAL PROPERTIES Tylosin is an antibiotic from the macrolide group, active against most gram-positive and some gram-negative bacteria, including staphylococci, streptococci, corynebacteria, clostridia, pasteurella, erysipelothrix, spirochetes, chlamydia, Treponema chiodysentery and mycoplasmas. When administered orally, the antibiotic is well absorbed from the gastrointestinal tract and penetrates almost all organs and tissues of the body. The highest levels of tylosin are achieved in the lungs, liver, mammary glands and kidneys. The therapeutic concentration of the antibiotic after a single administration of farmazin water-soluble powder remains in the body for 15-18 hours. In addition, due to the peculiarities of the mechanism of action, farmazin selectively accumulates in tissues with low pH values, that is, in areas of inflammation, providing a pronounced and targeted effect. Farmazin exhibits a nonspecific immunostimulating and immunomodulatory effect due to the inhibition of cytokines, activation of plasma cells and antibody production, activation of leukocyte hemotaxis and proliferation of lymphoid elements. Farmazin accumulates in extremely high concentrations in the lysosomes of neutrophils, ensuring the completion of phagocytosis and rapid disposal of bacterial pathogens. Tylosin is excreted from the body mainly in feces, in smaller quantities in urine and milk, and in laying birds - in eggs.
INDICATIONS Prescribed for the prevention and treatment of respiratory mycoplasmosis of birds, infectious sinusitis of turkeys, as well as the treatment of dysentery and gastroenterocolitis of bacterial etiology in pigs, bronchopneumonia of calves caused by pathogens sensitive to tylosin. To combat necrobacteriosis in cattle and small ruminants.
DOSES AND METHOD OF ADMINISTRATION Farmazin powder is used orally with drinking water. The antibiotic solution should be in the drinking bowls constantly throughout the entire period of use of Farmazin. First dissolve the required amount of farmazin in a small amount of water, adding water to the preparation. This solution is then diluted with water to the required concentration. Avoid exposing the aqueous solution of farmazin to direct sunlight. An antibiotic solution is prepared daily. For respiratory mycoplasmosis of birds and infectious sinusitis of turkeys, the drug is prescribed for prophylactic purposes in a dose of 1 g per 1 liter of water during the following periods of a bird’s life:
Species and group of birds Age of bird (days) Breeding poultry 1 – 5 28 – 29 56 – 57 140 – 141 Industrial poultry of egg breeds 1 – 3 28 – – Broilers 1 – 3 28 – – Turkeys 1 – 3 28 – 29 – –
For medicinal purposes, farmazin water-soluble powder is used in the following doses: for poultry - 1 g of the drug is dissolved in 1 liter of water and given to broilers - for 3 days, and for turkeys - for 5 days. During the treatment period, water containing farmazin is the only source of drinking for the bird. For dysentery and gastroenterocolitis of bacterial etiology in pigs, farmazin water-soluble powder is given in a dose of 0.5 g of the drug per 1 liter of water (or 10 mg per 1 kg of animal weight) for 3-10 days, depending on the degree of the disease. During the treatment period, water containing farmazin is the only source of drinking for pigs. For bronchopneumonia in calves, the drug is used at the rate of 10 mg of active substance per 1 kg of animal weight (drinked individually with water or milk) 2 times a day for 7-14 days. A solution of farmazin water-soluble powder is prepared based on the water needs of poultry and animals for 1 day. It is possible to use the drug in a mixture with feed in the same doses, but it is necessary to control feed consumption to ensure that animals or poultry receive a sufficient amount of farmazin. The most accessible method for this is to evenly mix the antibiotic with half the daily feed intake. The remaining half of the food should be fed after eating the antibiotic food. To combat necrobacteriosis in cattle and small ruminants, a solution of farmazin is used with a drug concentration of 200 g (1 package) per 100 liters of water. Livestock treatments are carried out using foot baths once a day for 3 days in a row, after which treatments can be repeated once every 2 days, depending on the severity of clinical symptoms and the degree of improvement.
SIDE EFFECTS Very rarely, allergic reactions in pigs are possible in the form of erythema, itching, respiratory phenomena, mild swelling with slight prolapse of the rectum, which quickly disappear after stopping the use of the drug.
CONTRAINDICATIONS Increased individual sensitivity to tylosin. It is prohibited to use Farmazin in laying hens and turkeys that produce eggs for human consumption. It is not recommended to prescribe farmazin water-soluble powder simultaneously with tiamulin, clindamycin, chloramphenicol, penicillins (especially ampicillin and oxacillin), cephalosporins and lincomycin due to a pronounced decrease in the antibacterial effect of tylosin.
SPECIAL INSTRUCTIONS Slaughter of calves for meat is permitted after 14 days, pigs and poultry - after 5 days after the last use of the drug. The meat of animals forcedly killed before the expiration of the specified period is used to feed carnivores or to produce meat and bone meal. Eggs of birds treated with farmazin are not eaten due to the risk of sensitization. If farmazin powder comes into contact with the surface of the skin, it is washed off with soapy water.
STORAGE CONDITIONS With precautions (list B). In a dry place, protected from light and inaccessible to children and animals, at a temperature of 5-25 ° C. Shelf life: 3 years.
Indications for use
For cats, the medicine is used according to strict indications.
Your veterinarian may prescribe an antibiotic for your cat in the following cases:
- bronchopneumonia, especially in advanced form;
- severe inflammation of the joints of a bacterial nature;
- dysentery;
- secondary bacterial infection against the background of a viral infection;
- severe purulent-inflammatory skin diseases, if there is no effectiveness from the use of other types of antibiotics.
In most cases, Farmazin 50 is prescribed to cats by a veterinarian when the use of other types of antibiotics is low.
The main area of use of this antibiotic is agriculture , where it allows you to quickly eliminate various diseases of pigs, goats, sheep, cows and poultry. With this treatment, it is possible to consume their meat, milk and eggs fairly quickly after its completion.
When is Farmazin used?
Farmazin 50 is used to treat:
— bronchopneumonia of large and small cattle, pigs, dogs and cats;
— mastitis in cattle;
— enzootic pneumonia, arthritis, dysentery, atrophic rhinitis of pigs;
— infectious agalactia of sheep and goats;
- skin infections.
— secondary infections in viral diseases.
is not recommended due to a pronounced decrease in the antibacterial effect of tylosin.
Directions for use, dosage for cats
The medicine is administered through an injection. The injection is given intramuscularly in the thigh using an insulin syringe. The dose for the animal is individually calculated by the veterinarian.
Most often, an antibiotic is administered at a dosage of 0.1-0.2 ml per 1 kg of cat weight per day. The injection is given once a day at the same time. The drug should be injected alternately into the right and left thigh. This is required to prevent the formation of compactions in tissues.
The medicine is administered by injection
The course of treatment is determined by a veterinarian and should not be interrupted arbitrarily by the cat’s owner.
After the animal’s condition improves, the prescribed course of injections is continued for as many days as recommended by the veterinarian. Otherwise, there is a high risk of re-development of the disease due to activation of the pathogen.
Contraindications and possible side effects
Side effects are rare if the dosage of the medication is followed. In some cases, it is possible to develop an allergy to the drug. Treatment is symptomatic.
Contraindications to the use of the composition are as follows:
- individual intolerance to the drug or hypersensitivity to it;
- use of other antibiotics;
- kitten feeding period.
Be sure to read:
Vasotope for cats: instructions, price and reviews
Pregnant cats are prescribed medication only if there is no other treatment that is safe for the offspring.
Special instructions, storage, price
In most cases, after proper use of Farmazin 500, there is no need for restrictive measures.
There is no provision for slaughtering broilers for meat before 35 days of age. More than five days have passed since the last antibiotic treatment.
Forcibly slaughtered replacement chickens under 9 weeks of age or turkey poults under a month old are not suitable for food. Therefore, we can say that there are no restrictions on the consumption of meat or eggs.
Farmazin 500 is a powder containing equal amounts of tylosin and the filler lactose.
It is packaged in polymer jars of 25 and 200 g or bags of 10 g. The cost of a ten-gram package is about 120 rubles, a two-hundred-gram package is approximately 1,250 rubles.
Be sure to read:
Treatment of animals and birds with Biovit-80 for infectious diseases: instructions and price
It is recommended to store the drug in a dark, dry place at a temperature of +5 to +25 degrees for no more than three years from the date of production.
Reviews from owners and veterinarians about the drug
Veterinarians speak positively about the medicine, but since it is more intended for farm animals, they do not use it for cats very often.
Cat owners, although the antibiotic has a quick therapeutic effect, usually do not really like it when their pets are prescribed this composition, since they have to give intramuscular injections.
Those who know how to easily administer medicine intramuscularly to a cat speak only positively about the product.
Description of the drug
A medicine used in veterinary medicine called Farmazin 200 is available in the form of a solution for intramuscular injections. The active component of the drug is tylosin. Belongs to antibiotics from the macrolide group. 1 ml of solution contains 200 mg of tylosin. In addition to the active ingredient, Farmazin 200 contains propylene glycol and purified water. The solution is transparent, the color is dark yellow.
Farmazin 200 is available in different packaging sizes. Depending on your needs, you can buy 50 or 100 ml of the drug. It is packaged in dark glass bottles, sealed with rubber caps, which are crimped on top with dark green aluminum caps.
The glass bottle has a label with basic information: name, composition, batch number and, of course, the expiration date of the medicine. The bottle with the drug is placed in a cardboard box. Instructions for the use of this veterinary drug are also placed there.
The shelf life of this veterinary product is 3 years. After opening the bottle, Farmazin 200 should be used within 4 weeks (28 days). When using directly, take the necessary precautions.
